Synovetin OA® targets canine osteoarthritis at its source for up to 1 full year of pain relief
Synovetin OA is a completely different arthritis treatment that acts on the driver of the disease itself—inflammation—not just symptoms. That means pain relief today that lasts up to 1 full year AND the potential to prevent future pain by delaying the joint damage caused by inflammation. Only Synovetin OA is designed to target the inflamed synovium and mitigate the cytokine cascade that leads to disease progression and joint destruction.1-3
















In the joint fluid of an arthritic joint, inflammatory cells drive pain and progression of the disease. Inflammation is the source of pain–where it begins. The inflammatory cells in inflamed joints produce substances that cause even more inflammation and damage to the joint. This is called “the vicious cycle of inflammation” and if left untreated, it causes ongoing inflammation, pain, and damage to the cartilage that lines the joint.
The effectiveness of Synovetin OA was studied in multiple clinical trials of dogs with elbow arthritis. Researchers evaluated Synovetin OA in its ability to relieve arthritis pain in dogs, such as lameness (limping), level of activity, and signs of pain during the year-long studies.
In most cases, you should begin to see improvement in your dog’s mobility within a few weeks, depending on the severity of arthritis. Some dog owners see results almost immediately, while in other instances of severe arthritis, it can be up to 2 months. This improvement should continue over time as Synovetin OA works inside the joint to reduce inflammation.
Synovetin OA is a treatment that consists of microscopic particles of the unique isotope tin-117m. These targeted particles emit a form of mild radiation energy that inactivates the harmful cells causing inflammation within the joint and the tissues surrounding the joint (called the synovium) and that drive the loss of cartilage. This activity helps to restore joint health and provides very long lasting pain relief without the systemic side effects that can commonly occur with daily and monthly dog arthritis drugs.
Synovetin OA is administered directly into the arthritic joint where it remains and works locally to eliminate inflammation–the driver of pain and progression of arthritis. It does not travel through the dog’s body and therefore causes no systemic side effects. This is in contrast to pain drugs such as daily NSAIDs or monthly injections, which are metabolized systemically in the dog’s body and have known, significant side effects.






